Prevention Studies
DAL-GENE-2: This study evaluates the potential of dalcetrapib to reduce the occurrence of fatal and non-fatal heart attacks in patients with a documented recent acute coronary syndrome (ACS) and the AA genotype at variant rs1967309 in the ADCY9 gene.
More information
Heart Failure Studies
CORCINCH-HF: This clinical study evaluates the safety and efficacy of the AccuCinch Ventricular Restoration System in patients with heart failure and reduced ejection fraction (HFrEF).
More information
EMPOWER: This clinical trial assesses the safety and efficacy of the Carillon Mitral Contour System in treating heart failure patients who have early-stage functional mitral regurgitation (FMR).
More information
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III: This study evaluates the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III heart failure patients (PROACTIVE-HF-2 Trial).
More information
Device Studies
ACURATE IDE: This study evaluates the safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for transcatheter aortic valve replacement (TAVR) in people with severe native aortic stenosis.
More information
ALLIANCE: This study establishes the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in people with symptomatic, severe, calcific aortic stenosis (AS).
More information
AMPLATZER PFO: This study confirms the safety and effectiveness of the AMPLATZER PFO Occluder in the post-approval setting.
More information
AVENTUS: This study evaluates the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in people with acute pulmonary embolism.
More Information
CATALYST: This clinical trial evaluates the safety and effectiveness of the Amulet device compared to novel oral anticoagulant (NOAC) therapy in patients with non-valvular atrial fibrillation at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy.
More information
COMPLETE TAVR: Among patients who have undergone a successful elective transfemoral TAVR, this study will determine whether a strategy of complete revascularization involving staged PCI using drug eluting stents to treat all suitable coronary lesions is superior to a strategy of medical therapy alone in reducing the composite outcome of cardiovascular death, new heart attack, ischemia driven revascularization or hospitalization.
More information
CONFORM: This study evaluates if the CLAAS® device is similar in safety and efficacy to the commercially available WATCHMAN® and Amulet™ left atrial appendage closure devices in patients with non-valvular atrial fibrillation.
More information
EDWARDS PASCAL CLASP IID/IIF Pivotal Clinical Trial: This study evaluates the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation.
More information
ENCIRCLE: This study will establish the safety and effectiveness of the SAPIEN M3 System in people with symptomatic, at least 3+ mitral regurgitation (MR), for whom commercially available surgical or transcatheter treatment options are deemed unsuitable.
More information
PEERLESS: This study compares the FlowTriever system to catheter-directed thrombolysis (CDT) for acute intermediate-high-risk pulmonary embolism (PE) and includes a non-randomized group made up of 150 subjects who are not able to receive thrombolytics.
More information
PROGRESS: This study’s objective is to establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve in subjects with moderate, calcific aortic stenosis.
More information
SPYRAL AFFIRM: This study seeks to determine the long-term safety, efficacy and durability of the Symplicity Spyral system in subjects treated with renal denervation. Watch a Simplicity Spyral Procedure Animation.
More Information
MyChart